Novel 1,3,4-oxadiazole thioether derivatives targeting thymidylate synthase as dual anticancer/antimicrobial agents. [electronic resource]
Producer: 20140408Description: 2286-2297 p. digitalISSN:- 1464-3391
- Anti-Infective Agents -- chemistry
- Antineoplastic Agents -- chemistry
- Cell Line, Tumor
- Crystallography, X-Ray
- Drug Screening Assays, Antitumor
- Enzyme Inhibitors -- chemistry
- Escherichia coli -- drug effects
- Humans
- Kinetics
- Microbial Sensitivity Tests
- Models, Molecular
- Oxadiazoles -- chemistry
- Quantitative Structure-Activity Relationship
- Structure-Activity Relationship
- Thermodynamics
- Thymidylate Synthase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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