Bexarotene cannot reduce amyloid beta plaques through inhibition of production of amyloid beta peptides: in silico and in vitro study. [electronic resource]
Producer: 20190321Description: 24329-24338 p. digitalISSN:- 1463-9084
- Amyloid Precursor Protein Secretases -- chemistry
- Amyloid beta-Peptides -- antagonists & inhibitors
- Bexarotene -- chemistry
- Computer Simulation
- Humans
- Models, Molecular
- Molecular Docking Simulation
- Molecular Dynamics Simulation
- PPAR gamma -- chemistry
- Plaque, Amyloid -- chemistry
- Protein Binding
- Protein Conformation
- Retinoid X Receptors -- chemistry
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Publication Type: Journal Article
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