Cytochrome P450 17A1 inhibitor abiraterone attenuates cellular growth of prostate cancer cells independently from androgen receptor signaling by modulation of oncogenic and apoptotic pathways. [electronic resource]
Producer: 20160927Description: 793-800 p. digitalISSN:- 1791-2423
- Androstenes -- pharmacology
- Apoptosis -- drug effects
- Caspase 3 -- metabolism
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cyclin-Dependent Kinase Inhibitor p21 -- metabolism
- Cytochrome P-450 Enzyme System -- drug effects
- Humans
- Inhibitor of Apoptosis Proteins -- metabolism
- Male
- Prostate -- drug effects
- Prostatic Neoplasms -- drug therapy
- Receptors, Androgen -- metabolism
- Signal Transduction -- drug effects
- Survivin
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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