O(6) -methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy with concomitant and adjuvant temozolomide. [electronic resource]
Producer: 20121119Description: 4545-54 p. digitalISSN:- 1097-0142
- Adult
- Aged
- Antineoplastic Agents, Alkylating -- therapeutic use
- Biomarkers, Tumor
- Brain Neoplasms -- genetics
- Carmustine -- therapeutic use
- Chemoradiotherapy
- Chemotherapy, Adjuvant
- Combined Modality Therapy
- DNA Methylation
- Dacarbazine -- analogs & derivatives
- Disease-Free Survival
- Female
- Glioblastoma -- genetics
- Humans
- Male
- Middle Aged
- O(6)-Methylguanine-DNA Methyltransferase -- biosynthesis
- Prognosis
- Promoter Regions, Genetic
- Temozolomide
No physical items for this record
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
There are no comments on this title.
Log in to your account to post a comment.