Bosentan, an endothelin receptor antagonist, ameliorates collagen-induced arthritis: the role of TNF-α in the induction of endothelin system genes. [electronic resource]
Producer: 20120724Description: 337-48 p. digitalISSN:- 1420-908X
- Adult
- Animals
- Antirheumatic Agents -- therapeutic use
- Arthritis, Experimental -- drug therapy
- Arthritis, Rheumatoid -- drug therapy
- Bosentan
- Cells, Cultured
- Cytokines -- metabolism
- Endothelin Receptor Antagonists
- Endothelin-1 -- genetics
- Female
- Gene Expression Profiling
- Humans
- Leukocytes, Mononuclear
- Lymph Nodes -- drug effects
- Male
- Methotrexate -- therapeutic use
- Mice
- Mice, Inbred DBA
- Middle Aged
- Oligonucleotide Array Sequence Analysis
- RNA, Messenger -- metabolism
- Sulfonamides -- therapeutic use
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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