Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements. [electronic resource]
Producer: 20130827Description: 247-56 p. digitalISSN:- 1474-9726
- Cells, Cultured
- Cellular Senescence -- genetics
- Centromere
- DNA Transposable Elements
- Epigenesis, Genetic
- Euchromatin
- Fibroblasts -- cytology
- Formaldehyde
- Gene Expression
- Gene Silencing
- Genome, Human
- Heterochromatin
- Humans
- Oligonucleotide Array Sequence Analysis
- Regulatory Elements, Transcriptional
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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