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5'-C-Malonyl RNA: Small Interfering RNAs Modified with 5'-Monophosphate Bioisostere Demonstrate Gene Silencing Activity. [electronic resource] by
- Zlatev, Ivan
- Foster, Donald J
- Liu, Jingxuan
- Charisse, Klaus
- Brigham, Benjamin
- Parmar, Rubina G
- Jadhav, Vasant
- Maier, Martin A
- Rajeev, Kallanthottathil G
- Egli, Martin
- Manoharan, Muthiah
Producer: 20161213
In:
ACS chemical biology vol. 11
Availability: No items available.
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Facile Synthesis, Geometry, and 2'-Substituent-Dependent in Vivo Activity of 5'-(E)- and 5'-(Z)-Vinylphosphonate-Modified siRNA Conjugates. [electronic resource] by
- Parmar, Rubina Giare
- Brown, Christopher R
- Matsuda, Shigeo
- Willoughby, Jennifer L S
- Theile, Christopher S
- Charissé, Klaus
- Foster, Donald J
- Zlatev, Ivan
- Jadhav, Vasant
- Maier, Martin A
- Egli, Martin
- Manoharan, Muthiah
- Rajeev, Kallanthottathil G
Producer: 20190225
In:
Journal of medicinal chemistry vol. 61
Availability: No items available.
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5'-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger. [electronic resource] by
- Kumar, Pawan
- Parmar, Rubina G
- Brown, Christopher R
- Willoughby, Jennifer L S
- Foster, Donald J
- Babu, I Ramesh
- Schofield, Sally
- Jadhav, Vasant
- Charisse, Klaus
- Nair, Jayaprakash K
- Rajeev, Kallanthottathil G
- Maier, Martin A
- Egli, Martin
- Manoharan, Muthiah
Producer: 20190604
In:
Chemical communications (Cambridge, England) vol. 55
Availability: No items available.
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Selection of GalNAc-conjugated siRNAs with limited off-target-driven rat hepatotoxicity. [electronic resource] by
- Janas, Maja M
- Schlegel, Mark K
- Harbison, Carole E
- Yilmaz, Vedat O
- Jiang, Yongfeng
- Parmar, Rubina
- Zlatev, Ivan
- Castoreno, Adam
- Xu, Huilei
- Shulga-Morskaya, Svetlana
- Rajeev, Kallanthottathil G
- Manoharan, Muthiah
- Keirstead, Natalie D
- Maier, Martin A
- Jadhav, Vasant
Producer: 20180320
In:
Nature communications vol. 9
Availability: No items available.
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Endosomolytic bioreducible poly(amido amine disulfide) polymer conjugates for the in vivo systemic delivery of siRNA therapeutics. [electronic resource] by
- Parmar, Rubina Giare
- Busuek, Marina
- Walsh, Eileen S
- Leander, Karen R
- Howell, Bonnie J
- Sepp-Lorenzino, Laura
- Kemp, Eric
- Crocker, Louis S
- Leone, Anthony
- Kochansky, Christopher J
- Carr, Brian A
- Garbaccio, Robert M
- Colletti, Steven L
- Wang, Weimin
Producer: 20140117
In:
Bioconjugate chemistry vol. 24
Availability: No items available.
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8.
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Novel endosomolytic poly(amido amine) polymer conjugates for systemic delivery of siRNA to hepatocytes in rodents and nonhuman primates. [electronic resource] by
- Parmar, Rubina Giare
- Poslusney, Micheal
- Busuek, Marina
- Williams, J Michael
- Garbaccio, Robert
- Leander, Karen
- Walsh, Eileen
- Howell, Bonnie
- Sepp-Lorenzino, Laura
- Riley, Sean
- Patel, Mihir
- Kemp, Eric
- Latham, Andrew
- Leone, Anthony
- Soli, Eric
- Burke, Rob S
- Carr, Brian
- Colletti, Steven L
- Wang, Weimin
Producer: 20150330
In:
Bioconjugate chemistry vol. 25
Availability: No items available.
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9.
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5'-(E)-Vinylphosphonate: A Stable Phosphate Mimic Can Improve the RNAi Activity of siRNA-GalNAc Conjugates. [electronic resource] by
- Parmar, Rubina
- Willoughby, Jennifer L S
- Liu, Jingxuan
- Foster, Donald J
- Brigham, Benjamin
- Theile, Christopher S
- Charisse, Klaus
- Akinc, Akin
- Guidry, Erin
- Pei, Yi
- Strapps, Walter
- Cancilla, Mark
- Stanton, Matthew G
- Rajeev, Kallanthottathil G
- Sepp-Lorenzino, Laura
- Manoharan, Muthiah
- Meyers, Rachel
- Maier, Martin A
- Jadhav, Vasant
Producer: 20170330
In:
Chembiochem : a European journal of chemical biology vol. 17
Availability: No items available.
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10.
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Improving the in vivo therapeutic index of siRNA polymer conjugates through increasing pH responsiveness. [electronic resource] by
- Guidry, Erin N
- Farand, Julie
- Soheili, Arash
- Parish, Craig A
- Kevin, Nancy J
- Pipik, Brenda
- Calati, Kathleen B
- Ikemoto, Nori
- Waldman, Jacob H
- Latham, Andrew H
- Howell, Bonnie J
- Leone, Anthony
- Garbaccio, Robert M
- Barrett, Stephanie E
- Parmar, Rubina Giare
- Truong, Quang T
- Mao, Bing
- Davies, Ian W
- Colletti, Steven L
- Sepp-Lorenzino, Laura
Producer: 20141103
In:
Bioconjugate chemistry vol. 25
Availability: No items available.
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11.
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Development of a liver-targeted siRNA delivery platform with a broad therapeutic window utilizing biodegradable polypeptide-based polymer conjugates. [electronic resource] by
- Barrett, Stephanie E
- Burke, Rob S
- Abrams, Marc T
- Bason, Carol
- Busuek, Marina
- Carlini, Edward
- Carr, Brian A
- Crocker, Louis S
- Fan, Haihong
- Garbaccio, Robert M
- Guidry, Erin N
- Heo, Jun H
- Howell, Bonnie J
- Kemp, Eric A
- Kowtoniuk, Robert A
- Latham, Andrew H
- Leone, Anthony M
- Lyman, Michael
- Parmar, Rubina G
- Patel, Mihir
- Pechenov, Sergey Y
- Pei, Tao
- Pudvah, Nicole T
- Raab, Conrad
- Riley, Sean
- Sepp-Lorenzino, Laura
- Smith, Sheri
- Soli, Eric D
- Staskiewicz, Steven
- Stern, Melissa
- Truong, Quang
- Vavrek, Marissa
- Waldman, Jacob H
- Walsh, Eileen S
- Williams, J Michael
- Young, Stephanie
- Colletti, Steven L
Producer: 20141222
In:
Journal of controlled release : official journal of the Controlled Release Society vol. 183
Availability: No items available.
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