Enantioselective determination of mexiletine and its metabolites p-hydroxymexiletine and hydroxymethylmexiletine in rat plasma by normal-phase liquid chromatography-tandem mass spectrometry: application to pharmacokinetics. [electronic resource]
Producer: 20091102Description: 648-56 p. digitalISSN:- 1520-636X
- Animals
- Anti-Arrhythmia Agents
- Chromatography, High Pressure Liquid -- methods
- Chromatography, Liquid
- Culture Media
- Drugs, Chinese Herbal -- analysis
- Male
- Mass Spectrometry
- Mexiletine -- analogs & derivatives
- Rats
- Rats, Wistar
- Spectrometry, Fluorescence
- Spectrometry, Mass, Electrospray Ionization -- methods
- Spectrophotometry, Ultraviolet
- Tandem Mass Spectrometry -- methods
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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