The heat-shock response co-inducer arimoclomol protects against retinal degeneration in rhodopsin retinitis pigmentosa. [electronic resource]
Producer: 20141021Description: e1236 p. digitalISSN:- 2041-4889
- Animals
- Cell Line
- Cell Survival -- drug effects
- Cytoprotection
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Electroretinography
- Heat-Shock Response -- drug effects
- Humans
- Hydroxylamines -- pharmacology
- Mutation
- Photoreceptor Cells, Vertebrate -- drug effects
- Rats
- Rats, Sprague-Dawley
- Rats, Transgenic
- Retinal Degeneration -- genetics
- Retinitis Pigmentosa -- genetics
- Rhodopsin -- deficiency
- Time Factors
- Transfection
- Unfolded Protein Response -- drug effects
- Vision, Ocular -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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