Binding effect and design of a competitive inhibitory peptide for HMG-CoA reductase through modeling of an active peptide backbone. [electronic resource]
Producer: 20080428Description: 1309-18 p. digitalISSN:- 1464-3391
- Binding, Competitive
- Circular Dichroism
- Databases, Protein
- Drug Design
- Hydroxymethylglutaryl CoA Reductases -- chemistry
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- chemical synthesis
- Models, Biological
- Models, Molecular
- Peptides -- chemical synthesis
- Protein Binding
- Protein Denaturation
- Protein Folding
- Protein Structure, Tertiary
- Structure-Activity Relationship
- Temperature
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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