Progerin expression disrupts critical adult stem cell functions involved in tissue repair. [electronic resource]
Producer: 20150724Description: 1049-63 p. digitalISSN:- 1945-4589
- Adolescent
- Adult
- Adult Stem Cells -- drug effects
- Aged
- Cell Membrane -- metabolism
- Cell Movement
- Cell Proliferation
- Child
- Enzyme Inhibitors -- pharmacology
- Farnesyltranstransferase -- antagonists & inhibitors
- Gene Expression Regulation
- HEK293 Cells
- Humans
- Lamin Type A
- Male
- Membrane Fluidity
- Mesenchymal Stem Cells -- drug effects
- Middle Aged
- Nuclear Proteins -- genetics
- Protein Precursors -- genetics
- RNA, Messenger -- metabolism
- Regeneration -- drug effects
- Signal Transduction
- Time Factors
- Transfection
- Young Adult
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Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
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