The JAK inhibitor ruxolitinib reduces inflammation in an ILC3-independent model of innate immune colitis. [electronic resource]
Producer: 20190723Description: 1454-1465 p. digitalISSN:- 1935-3456
- Animals
- Colitis -- drug therapy
- Disease Models, Animal
- Epithelial Cells -- drug effects
- Immunity, Innate -- drug effects
- Inflammation -- drug therapy
- Inflammatory Bowel Diseases -- drug therapy
- Intestinal Mucosa -- drug effects
- Janus Kinase Inhibitors -- pharmacology
- Janus Kinases -- antagonists & inhibitors
- Lymphocytes -- drug effects
- Mice
- Mice, Inbred C57BL
- Nitriles
- Pyrazoles -- pharmacology
- Pyrimidines
- Tumor Necrosis Factors -- immunology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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