Characterization of the neutralizing activity of three anti-human TNF monoclonal antibodies and prediction of their TNF epitopes by molecular modeling and mutant protein approach. [electronic resource]
Producer: 20060718Description: 177-83 p. digitalISSN:- 0165-2478
- Antibodies, Monoclonal -- immunology
- Binding Sites, Antibody
- Blotting, Western
- Computer Simulation
- Cytotoxicity, Immunologic
- Dose-Response Relationship, Drug
- Enzyme-Linked Immunosorbent Assay
- Epitope Mapping
- Epitopes
- Feasibility Studies
- Intercellular Adhesion Molecule-1 -- metabolism
- Models, Molecular
- Mutation
- NF-kappa B -- physiology
- Tumor Necrosis Factor-alpha -- immunology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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