The progesterone derivative dydrogesterone down-regulates neurokinin 1 receptor expression on lymphocytes, induces a Th2 skew and exerts hypoalgesic effects in mice. [electronic resource]
Producer: 20070118Description: 159-67 p. digitalISSN:- 0946-2716
- Animals
- Cells, Cultured
- Cytokines -- biosynthesis
- Down-Regulation -- drug effects
- Dydrogesterone -- pharmacology
- Female
- Inflammation
- Lymphocytes -- drug effects
- Mast Cells -- cytology
- Mice
- Mice, Inbred CBA
- Neurotransmitter Agents -- metabolism
- Pain Threshold -- drug effects
- Receptors, Neurokinin-1 -- drug effects
- Substance P -- metabolism
- Th2 Cells -- drug effects
- Uterus -- cytology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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