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Potent and selective oxindole-based vasopressin 1b receptor antagonists with improved pharmacokinetic properties. [electronic resource] by
- Oost, Thorsten
- Backfisch, Gisela
- Bhowmik, Swati
- van Gaalen, Marcel M
- Geneste, Hervé
- Hornberger, Wilfried
- Lubisch, Wilfried
- Netz, Astrid
- Unger, Liliane
- Wernet, Wolfgang
Producer: 20111122
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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6.
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Design, synthesis and evaluation of MCH receptor 1 antagonists--Part II: Optimization of pyridazines toward reduced phospholipidosis and hERG inhibition. [electronic resource] by
- Roth, Gerald J
- Heckel, Armin
- Kley, Jörg T
- Lehmann, Thorsten
- Müller, Stephan G
- Oost, Thorsten
- Rudolf, Klaus
- Arndt, Kirsten
- Budzinski, Ralph
- Lenter, Martin
- Lotz, Ralf R H
- Schindler, Marcus
- Thomas, Leo
- Stenkamp, Dirk
Producer: 20160412
In:
Bioorganic & medicinal chemistry letters vol. 25
Availability: No items available.
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7.
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Design, synthesis and evaluation of MCH receptor 1 antagonists--Part III: Discovery of pre-clinical development candidate BI 186908. [electronic resource] by
- Oost, Thorsten
- Heckel, Armin
- Kley, Jörg T
- Lehmann, Thorsten
- Müller, Stephan
- Roth, Gerald J
- Rudolf, Klaus
- Arndt, Kirsten
- Budzinski, Ralph
- Lenter, Martin
- Lotz, Ralf R H
- Maier, Gerd-Michael
- Markert, Michael
- Thomas, Leo
- Stenkamp, Dirk
Producer: 20160412
In:
Bioorganic & medicinal chemistry letters vol. 25
Availability: No items available.
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8.
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Potent, selective inhibitors of protein tyrosine phosphatase 1B. [electronic resource] by
- Xin, Zhili
- Oost, Thorsten K
- Abad-Zapatero, Cele
- Hajduk, Philip J
- Pei, Zhonghua
- Szczepankiewicz, Bruce G
- Hutchins, Charles W
- Ballaron, Steve J
- Stashko, Mike A
- Lubben, Tom
- Trevillyan, James M
- Jirousek, Mike R
- Liu, Gang
Producer: 20040217
In:
Bioorganic & medicinal chemistry letters vol. 13
Availability: No items available.
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9.
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Design, synthesis and evaluation of MCH receptor 1 antagonists--Part I: Optimization of HTS hits towards an in vivo efficacious tool compound BI 414. [electronic resource] by
- Müller, Stephan G
- Heckel, Armin
- Kley, Jörg T
- Lehmann, Thorsten
- Lustenberger, Philipp
- Oost, Thorsten
- Roth, Gerald J
- Rudolf, Klaus
- Arndt, Kirsten
- Lenter, Martin
- Lotz, Ralf R H
- Maier, Gerd-Michael
- Markert, Michael
- Schindler, Marcus
- Stenkamp, Dirk
Producer: 20160412
In:
Bioorganic & medicinal chemistry letters vol. 25
Availability: No items available.
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10.
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Discovery of a potent and selective Bcl-2 inhibitor using SAR by NMR. [electronic resource] by
- Petros, Andrew M
- Huth, Jeffrey R
- Oost, Thorsten
- Park, Cheol-Min
- Ding, Hong
- Wang, Xilu
- Zhang, Haichao
- Nimmer, Paul
- Mendoza, Renaldo
- Sun, Chaohong
- Mack, Jamey
- Walter, Karl
- Dorwin, Sarah
- Gramling, Emily
- Ladror, Uri
- Rosenberg, Saul H
- Elmore, Steven W
- Fesik, Stephen W
- Hajduk, Philip J
Producer: 20110329
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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11.
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Discovery of potent antagonists of the antiapoptotic protein XIAP for the treatment of cancer. [electronic resource] by
- Oost, Thorsten K
- Sun, Chaohong
- Armstrong, Robert C
- Al-Assaad, Ali-Samer
- Betz, Stephen F
- Deckwerth, Thomas L
- Ding, Hong
- Elmore, Steven W
- Meadows, Robert P
- Olejniczak, Edward T
- Oleksijew, Andrew
- Oltersdorf, Tilman
- Rosenberg, Saul H
- Shoemaker, Alexander R
- Tomaselli, Kevin J
- Zou, Hua
- Fesik, Stephen W
Producer: 20040924
In:
Journal of medicinal chemistry vol. 47
Availability: No items available.
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12.
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Discovery and structure-activity relationship of antagonists of B-cell lymphoma 2 family proteins with chemopotentiation activity in vitro and in vivo. [electronic resource] by
- Wendt, Michael D
- Shen, Wang
- Kunzer, Aaron
- McClellan, William J
- Bruncko, Milan
- Oost, Thorsten K
- Ding, Hong
- Joseph, Mary K
- Zhang, Haichao
- Nimmer, Paul M
- Ng, Shi-Chung
- Shoemaker, Alexander R
- Petros, Andrew M
- Oleksijew, Anatol
- Marsh, Kennan
- Bauch, Joy
- Oltersdorf, Tilman
- Belli, Barbara A
- Martineau, Darlene
- Fesik, Stephen W
- Rosenberg, Saul H
- Elmore, Steven W
Producer: 20060329
In:
Journal of medicinal chemistry vol. 49
Availability: No items available.
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13.
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Studies leading to potent, dual inhibitors of Bcl-2 and Bcl-xL. [electronic resource] by
- Bruncko, Milan
- Oost, Thorsten K
- Belli, Barbara A
- Ding, Hong
- Joseph, Mary K
- Kunzer, Aaron
- Martineau, Darlene
- McClellan, William J
- Mitten, Michael
- Ng, Shi-Chung
- Nimmer, Paul M
- Oltersdorf, Tilman
- Park, Cheol-Min
- Petros, Andrew M
- Shoemaker, Alexander R
- Song, Xiaohong
- Wang, Xilu
- Wendt, Michael D
- Zhang, Haichao
- Fesik, Stephen W
- Rosenberg, Saul H
- Elmore, Steven W
Producer: 20070327
In:
Journal of medicinal chemistry vol. 50
Availability: No items available.
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