NLRP3 inflammasome knockout mice are protected against ischemic but not cisplatin-induced acute kidney injury. [electronic resource]
Producer: 20131104Description: 465-72 p. digitalISSN:- 1521-0103
- Acute Kidney Injury -- chemically induced
- Animals
- Antineoplastic Agents
- Carrier Proteins -- genetics
- Caspase 1 -- metabolism
- Caspases -- metabolism
- Cell Line, Tumor
- Cisplatin
- Enzyme-Linked Immunosorbent Assay
- Interleukin-1alpha -- metabolism
- Interleukin-1beta -- metabolism
- Ischemia -- complications
- Kidney -- pathology
- Kidney Tubules, Proximal -- pathology
- Macrophages -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- NLR Family, Pyrin Domain-Containing 3 Protein
- Neutrophil Infiltration -- genetics
- Renal Circulation -- physiology
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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