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DNA interstrand crosslinking agents: synthesis, DNA interactions, and cytotoxicity of dimeric achiral seco-amino-CBI and conjugates of achiral seco-amino-CBI with pyrrolobenzodiazepine (PBD). [electronic resource] by
- Purnell, Bethany
- Sato, Atsushi
- O'kelley, Amanda
- Price, Carly
- Summerville, Kaitlin
- Hudson, Stephen
- O'hare, Caroline
- Kiakos, Konstantinos
- Asao, Tetsuji
- Lee, Moses
- Hartley, John A
Producer: 20061222
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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Binding of f-PIP, a pyrrole- and imidazole-containing triamide, to the inverted CCAAT box-2 of the topoisomerase IIalpha promoter and modulation of gene expression in cells. [electronic resource] by
- Le, N Minh
- Sielaff, Alan M
- Cooper, Amanda J
- Mackay, Hilary
- Brown, Toni
- Kotecha, Minal
- O'Hare, Caroline
- Hochhauser, Daniel
- Lee, Moses
- Hartley, John A
Producer: 20070216
In:
Bioorganic & medicinal chemistry letters vol. 16
Availability: No items available.
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4.
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Modulation of topoisomerase IIalpha expression by a DNA sequence-specific polyamide. [electronic resource] by
- Hochhauser, Daniel
- Kotecha, Minal
- O'hare, Caroline
- Morris, Peter J
- Hartley, Janet M
- Taherbhai, Zarmeen
- Harris, Dorothy
- Forni, Claudia
- Mantovani, Roberto
- Lee, Moses
- Hartley, John A
Producer: 20070316
In:
Molecular cancer therapeutics vol. 6
Availability: No items available.
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5.
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Design of a hairpin polyamide, ZT65B, for targeting the inverted CCAAT box (ICB) site in the multidrug resistant (MDR1) gene. [electronic resource] by
- Buchmueller, Karen L
- Taherbhai, Zarmeen
- Howard, Cameron M
- Bailey, Suzanna L
- Nguyen, Binh
- O'Hare, Caroline
- Hochhauser, Daniel
- Hartley, John A
- Wilson, W David
- Lee, Moses
Producer: 20061122
In:
Chembiochem : a European journal of chemical biology vol. 6
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6.
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Targeting the inverted CCAAT Box-2 of the topoisomerase IIalpha gene: DNA sequence selective recognition by a polyamide-intercalator as a staggered dimer. [electronic resource] by
- Mackay, Hilary
- Brown, Toni
- Sexton, Jim S
- Kotecha, Minal
- Nguyen, Binh
- Wilson, W David
- Kluza, Jerome
- Savic, Boris
- O'Hare, Caroline
- Hochhauser, Daniel
- Lee, Moses
- Hartley, John A
Producer: 20080603
In:
Bioorganic & medicinal chemistry vol. 16
Availability: No items available.
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7.
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Physical and structural basis for the strong interactions of the -ImPy- central pairing motif in the polyamide f-ImPyIm. [electronic resource] by
- Buchmueller, Karen L
- Bailey, Suzanna L
- Matthews, David A
- Taherbhai, Zarmeen T
- Register, Janna K
- Davis, Zachary S
- Bruce, Chrystal D
- O'Hare, Caroline
- Hartley, John A
- Lee, Moses
Producer: 20070119
In:
Biochemistry vol. 45
Availability: No items available.
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8.
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Modifying the N-terminus of polyamides: PyImPyIm has improved sequence specificity over f-ImPyIm. [electronic resource] by
- Brown, Toni
- Mackay, Hilary
- Turlington, Mark
- Sutterfield, Arden
- Smith, Traci
- Sielaff, Alan
- Westrate, Laura
- Bruce, Chrystal
- Kluza, Jerome
- O'Hare, Caroline
- Nguyen, Binh
- Wilson, W David
- Hartley, John A
- Lee, Moses
Producer: 20080826
In:
Bioorganic & medicinal chemistry vol. 16
Availability: No items available.
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9.
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Synthesis and biophysical evaluation of minor-groove binding C-terminus modified pyrrole and imidazole triamide analogs of distamycin. [electronic resource] by
- Brown, Toni
- Taherbhai, Zarmeen
- Sexton, Jim
- Sutterfield, Arden
- Turlington, Mark
- Jones, Justin
- Stallings, Lindsay
- Stewart, Michelle
- Buchmueller, Karen
- Mackay, Hilary
- O'hare, Caroline
- Kluza, Jerome
- Nguyen, Binh
- Wilson, David
- Lee, Moses
- Hartley, John A
Producer: 20070220
In:
Bioorganic & medicinal chemistry vol. 15
Availability: No items available.
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10.
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Sequence specific and high affinity recognition of 5'-ACGCGT-3' by rationally designed pyrrole-imidazole H-pin polyamides: thermodynamic and structural studies. [electronic resource] by
- Mackay, Hilary
- Brown, Toni
- Uthe, Peter B
- Westrate, Laura
- Sielaff, Alan
- Jones, Justin
- Lajiness, James P
- Kluza, Jerome
- O'Hare, Caroline
- Nguyen, Binh
- Davis, Zach
- Bruce, Chrystal
- Wilson, W David
- Hartley, John A
- Lee, Moses
Producer: 20081215
In:
Bioorganic & medicinal chemistry vol. 16
Availability: No items available.
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11.
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Synthesis and evaluation of an intercalator-polyamide hairpin designed to target the inverted CCAAT box 2 in the topoisomerase IIalpha promoter. [electronic resource] by
- Flores, Lloyd V
- Staples, Andrew M
- Mackay, Hilary
- Howard, Cameron M
- Uthe, Peter B
- Sexton, Jim S
- Buchmueller, Karen L
- Wilson, W David
- O'Hare, Caroline
- Kluza, Jerome
- Hochhauser, Daniel
- Hartley, John A
- Lee, Moses
Producer: 20070108
In:
Chembiochem : a European journal of chemical biology vol. 7
Availability: No items available.
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