Mucopolysaccharidosis I cats mount a cytotoxic T lymphocyte response after neonatal gene therapy that can be blocked with CTLA4-Ig. [electronic resource]
Producer: 20060905Description: 5-13 p. digitalISSN:- 1525-0016
- Abatacept
- Animals
- Animals, Newborn
- Cats
- Dogs
- Dose-Response Relationship, Drug
- Genetic Therapy -- methods
- Genetic Vectors -- genetics
- Glycosaminoglycans -- metabolism
- Iduronidase -- deficiency
- Immune Tolerance -- drug effects
- Immunoconjugates -- pharmacology
- Immunosuppressive Agents -- pharmacology
- Liver -- drug effects
- Mice
- Mucopolysaccharidosis I -- genetics
- T-Lymphocytes, Cytotoxic -- immunology
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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