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Novel potent dual inhibitors of CK2 and Pim kinases with antiproliferative activity against cancer cells. [electronic resource] by
- Pierre, Fabrice
- Regan, Collin F
- Chevrel, Marie-Claire
- Siddiqui-Jain, Adam
- Macalino, Diwata
- Streiner, Nicole
- Drygin, Denis
- Haddach, Mustapha
- O'Brien, Sean E
- Rice, William G
- Ryckman, David M
Producer: 20121011
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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7.
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Unprecedented selectivity and structural determinants of a new class of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. [electronic resource] by
- Battistutta, Roberto
- Cozza, Giorgio
- Pierre, Fabrice
- Papinutto, Elena
- Lolli, Graziano
- Sarno, Stefania
- O'Brien, Sean E
- Siddiqui-Jain, Adam
- Haddach, Mustapha
- Anderes, Kenna
- Ryckman, David M
- Meggio, Flavio
- Pinna, Lorenzo A
Producer: 20111207
In:
Biochemistry vol. 50
Availability: No items available.
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8.
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7-(4H-1,2,4-Triazol-3-yl)benzo[c][2,6]naphthyridines: a novel class of Pim kinase inhibitors with potent cell antiproliferative activity. [electronic resource] by
- Pierre, Fabrice
- Stefan, Eric
- Nédellec, Anne-Sophie
- Chevrel, Marie-Claire
- Regan, Collin F
- Siddiqui-Jain, Adam
- Macalino, Diwata
- Streiner, Nicole
- Drygin, Denis
- Haddach, Mustapha
- O'Brien, Sean E
- Anderes, Kenna
- Ryckman, David M
Producer: 20120213
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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Novel potent pyrimido[4,5-c]quinoline inhibitors of protein kinase CK2: SAR and preliminary assessment of their analgesic and anti-viral properties. [electronic resource] by
- Pierre, Fabrice
- O'Brien, Sean E
- Haddach, Mustapha
- Bourbon, Pauline
- Schwaebe, Michael K
- Stefan, Eric
- Darjania, Levan
- Stansfield, Ryan
- Ho, Caroline
- Siddiqui-Jain, Adam
- Streiner, Nicole
- Rice, William G
- Anderes, Kenna
- Ryckman, David M
Producer: 20110705
In:
Bioorganic & medicinal chemistry letters vol. 21
Availability: No items available.
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10.
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Combined inhibition of EGFR and CK2 augments the attenuation of PI3K-Akt-mTOR signaling and the killing of cancer cells. [electronic resource] by
- Bliesath, Joshua
- Huser, Nanni
- Omori, Mayuko
- Bunag, Daniel
- Proffitt, Chris
- Streiner, Nicole
- Ho, Caroline
- Siddiqui-Jain, Adam
- O'Brien, Sean E
- Lim, John K C
- Ryckman, David M
- Anderes, Kenna
- Rice, William G
- Drygin, Denis
Producer: 20120803
In:
Cancer letters vol. 322
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11.
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CX-4945, an orally bioavailable selective inhibitor of protein kinase CK2, inhibits prosurvival and angiogenic signaling and exhibits antitumor efficacy. [electronic resource] by
- Siddiqui-Jain, Adam
- Drygin, Denis
- Streiner, Nicole
- Chua, Peter
- Pierre, Fabrice
- O'Brien, Sean E
- Bliesath, Josh
- Omori, Mayuko
- Huser, Nanni
- Ho, Caroline
- Proffitt, Chris
- Schwaebe, Michael K
- Ryckman, David M
- Rice, William G
- Anderes, Kenna
Producer: 20110120
In:
Cancer research vol. 70
Availability: No items available.
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12.
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Synthesis and SAR of inhibitors of protein kinase CK2: novel tricyclic quinoline analogs. [electronic resource] by
- Haddach, Mustapha
- Pierre, Fabrice
- Regan, Collin F
- Borsan, Cosmin
- Michaux, Jerome
- Stefan, Eric
- Kerdoncuff, Pauline
- Schwaebe, Michael K
- Chua, Peter C
- Siddiqui-Jain, Adam
- Macalino, Diwata
- Drygin, Denis
- O'Brien, Sean E
- Rice, William G
- Ryckman, David M
Producer: 20120803
In:
Bioorganic & medicinal chemistry letters vol. 22
Availability: No items available.
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13.
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CK2 inhibitor CX-4945 suppresses DNA repair response triggered by DNA-targeted anticancer drugs and augments efficacy: mechanistic rationale for drug combination therapy. [electronic resource] by
- Siddiqui-Jain, Adam
- Bliesath, Joshua
- Macalino, Diwata
- Omori, Mayuko
- Huser, Nanni
- Streiner, Nicole
- Ho, Caroline B
- Anderes, Kenna
- Proffitt, Chris
- O'Brien, Sean E
- Lim, John K C
- Von Hoff, Daniel D
- Ryckman, David M
- Rice, William G
- Drygin, Denis
Producer: 20121016
In:
Molecular cancer therapeutics vol. 11
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14.
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Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth. [electronic resource] by
- Drygin, Denis
- Lin, Amy
- Bliesath, Josh
- Ho, Caroline B
- O'Brien, Sean E
- Proffitt, Chris
- Omori, Mayuko
- Haddach, Mustapha
- Schwaebe, Michael K
- Siddiqui-Jain, Adam
- Streiner, Nicole
- Quin, Jaclyn E
- Sanij, Elaine
- Bywater, Megan J
- Hannan, Ross D
- Ryckman, David
- Anderes, Kenna
- Rice, William G
Producer: 20110427
In:
Cancer research vol. 71
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15.
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Discovery of CX-5461, the First Direct and Selective Inhibitor of RNA Polymerase I, for Cancer Therapeutics. [electronic resource] by
- Haddach, Mustapha
- Schwaebe, Michael K
- Michaux, Jerome
- Nagasawa, Johnny
- O'Brien, Sean E
- Whitten, Jeffrey P
- Pierre, Fabrice
- Kerdoncuff, Pauline
- Darjania, Levan
- Stansfield, Ryan
- Drygin, Denis
- Anderes, Kenna
- Proffitt, Chris
- Bliesath, Josh
- Siddiqui-Jain, Adam
- Omori, May
- Huser, Nanni
- Rice, William G
- Ryckman, David M
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 3
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16.
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Discovery of CX-6258. A Potent, Selective, and Orally Efficacious pan-Pim Kinases Inhibitor. [electronic resource] by
- Haddach, Mustapha
- Michaux, Jerome
- Schwaebe, Michael K
- Pierre, Fabrice
- O'Brien, Sean E
- Borsan, Cosmin
- Tran, Joe
- Raffaele, Nicholas
- Ravula, Suchitra
- Drygin, Denis
- Siddiqui-Jain, Adam
- Darjania, Levan
- Stansfield, Ryan
- Proffitt, Chris
- Macalino, Diwata
- Streiner, Nicole
- Bliesath, Joshua
- Omori, May
- Whitten, Jeffrey P
- Anderes, Kenna
- Rice, William G
- Ryckman, David M
Producer: 20140605
In:
ACS medicinal chemistry letters vol. 3
Availability: No items available.
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17.
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Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer. [electronic resource] by
- Pierre, Fabrice
- Chua, Peter C
- O'Brien, Sean E
- Siddiqui-Jain, Adam
- Bourbon, Pauline
- Haddach, Mustapha
- Michaux, Jerome
- Nagasawa, Johnny
- Schwaebe, Michael K
- Stefan, Eric
- Vialettes, Anne
- Whitten, Jeffrey P
- Chen, Ta Kung
- Darjania, Levan
- Stansfield, Ryan
- Bliesath, Joshua
- Drygin, Denis
- Ho, Caroline
- Omori, May
- Proffitt, Chris
- Streiner, Nicole
- Rice, William G
- Ryckman, David M
- Anderes, Kenna
Producer: 20120228
In:
Molecular and cellular biochemistry vol. 356
Availability: No items available.
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18.
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Discovery and SAR of 5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid (CX-4945), the first clinical stage inhibitor of protein kinase CK2 for the treatment of cancer. [electronic resource] by
- Pierre, Fabrice
- Chua, Peter C
- O'Brien, Sean E
- Siddiqui-Jain, Adam
- Bourbon, Pauline
- Haddach, Mustapha
- Michaux, Jerome
- Nagasawa, Johnny
- Schwaebe, Michael K
- Stefan, Eric
- Vialettes, Anne
- Whitten, Jeffrey P
- Chen, Ta Kung
- Darjania, Levan
- Stansfield, Ryan
- Anderes, Kenna
- Bliesath, Josh
- Drygin, Denis
- Ho, Caroline
- Omori, May
- Proffitt, Chris
- Streiner, Nicole
- Trent, Katy
- Rice, William G
- Ryckman, David M
Producer: 20110307
In:
Journal of medicinal chemistry vol. 54
Availability: No items available.
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19.
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Scalable production of large quantities of defect-free few-layer graphene by shear exfoliation in liquids. [electronic resource] by
- Paton, Keith R
- Varrla, Eswaraiah
- Backes, Claudia
- Smith, Ronan J
- Khan, Umar
- O'Neill, Arlene
- Boland, Conor
- Lotya, Mustafa
- Istrate, Oana M
- King, Paul
- Higgins, Tom
- Barwich, Sebastian
- May, Peter
- Puczkarski, Pawel
- Ahmed, Iftikhar
- Moebius, Matthias
- Pettersson, Henrik
- Long, Edmund
- Coelho, João
- O'Brien, Sean E
- McGuire, Eva K
- Sanchez, Beatriz Mendoza
- Duesberg, Georg S
- McEvoy, Niall
- Pennycook, Timothy J
- Downing, Clive
- Crossley, Alison
- Nicolosi, Valeria
- Coleman, Jonathan N
Producer: 20140707
In:
Nature materials vol. 13
Availability: No items available.
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