Pancreatic β cells overexpressing hIAPP impaired mitophagy and unbalanced mitochondrial dynamics. [electronic resource]
Producer: 20200330Description: 481 p. digitalISSN:- 2041-4889
- Animals
- Apoptosis
- Cell Line, Tumor
- Endoplasmic Reticulum Stress
- Humans
- Insulin-Secreting Cells -- metabolism
- Islet Amyloid Polypeptide -- genetics
- Mechanistic Target of Rapamycin Complex 1 -- metabolism
- Mitochondria -- metabolism
- Mitochondrial Dynamics
- Mitophagy
- Proteolysis
- Rats
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- Tuberous Sclerosis Complex 2 Protein -- metabolism
- Tyrosine -- analogs & derivatives
- Ubiquitination
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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