Molecular dissection of effector mechanisms of RAS-mediated resistance to anti-EGFR antibody therapy. [electronic resource]
Producer: 20180411Description: 45898-45917 p. digitalISSN:- 1949-2553
- Antineoplastic Agents, Immunological -- pharmacology
- Apoptosis -- drug effects
- Biomarkers
- Cell Line, Tumor
- Colorectal Neoplasms -- drug therapy
- Drug Resistance, Neoplasm -- genetics
- ErbB Receptors -- antagonists & inhibitors
- Exons
- Genes, ras
- Humans
- Mitogen-Activated Protein Kinases
- Mutation
- Odds Ratio
- Phosphatidylinositol 3-Kinases -- metabolism
- Proto-Oncogene Proteins c-akt -- metabolism
- Proto-Oncogene Proteins c-bcl-2 -- genetics
- Signal Transduction -- drug effects
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Publication Type: Journal Article
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