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A UGT2B10 splicing polymorphism common in african populations may greatly increase drug exposure. [electronic resource] by
- Fowler, Stephen
- Kletzl, Heidemarie
- Finel, Moshe
- Manevski, Nenad
- Schmid, Paul
- Tuerck, Dietrich
- Norcross, Roger D
- Hoener, Marius C
- Spleiss, Olivia
- Iglesias, Victor A
Producer: 20150708
In:
The Journal of pharmacology and experimental therapeutics vol. 352
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The selective antagonist EPPTB reveals TAAR1-mediated regulatory mechanisms in dopaminergic neurons of the mesolimbic system. [electronic resource] by
- Bradaia, Amyaouch
- Trube, Gerhard
- Stalder, Henri
- Norcross, Roger D
- Ozmen, Laurence
- Wettstein, Joseph G
- Pinard, Audrée
- Buchy, Danièle
- Gassmann, Martin
- Hoener, Marius C
- Bettler, Bernhard
Producer: 20100114
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 106
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7.
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Discovery of benzoylpiperazines as a novel class of potent and selective GlyT1 inhibitors. [electronic resource] by
- Pinard, Emmanuel
- Alberati, Daniela
- Borroni, Edilio
- Fischer, Holger
- Hainzl, Dominik
- Jolidon, Synèse
- Moreau, Jean-Luc
- Narquizian, Robert
- Nettekoven, Matthias
- Norcross, Roger D
- Stalder, Henri
- Thomas, Andrew W
Producer: 20081014
In:
Bioorganic & medicinal chemistry letters vol. 18
Availability: No items available.
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8.
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Discovery and Characterization of 2-Aminooxazolines as Highly Potent, Selective, and Orally Active TAAR1 Agonists. [electronic resource] by
- Galley, Guido
- Beurier, Angélica
- Décoret, Guillaume
- Goergler, Annick
- Hutter, Roman
- Mohr, Susanne
- Pähler, Axel
- Schmid, Philipp
- Türck, Dietrich
- Unger, Robert
- Zbinden, Katrin Groebke
- Hoener, Marius C
- Norcross, Roger D
Producer: 20160317
In:
ACS medicinal chemistry letters vol. 7
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Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1 Financial support was provided by the EPSRC (GR/L41646), Cambridge Commonwealth Trust (Scholarship to M.J.C.), EC (Marie Curie Postdoctoral Fellowship to J.L.A.), DFG (Postdoctoral Fellowship to T.T.), NSERC-Canada (Postdoctoral Fellowship to R.M.O.), Churchill College (Research Fellowship to D.J.W.), Kingapos;s College and Sims Fund, Cambridge (Scholarship to D.Y.K.C.). We also thank Merck and AstraZeneca Pharmaceuticals for generous support, and Dr. Anne Butlin (AZ) and Dr. Nick Bampos (Cambridge) for valuable assistance. [electronic resource] by
- Paterson, Ian
- Chen, David Y.-K
- Coster, Mark J
- Aceña, Jose L
- Bach, Jordi
- Gibson, Karl R
- Keown, Linda E
- Oballa, Renata M
- Trieselmann, Thomas
- Wallace, Debra J
- Hodgson, Andrew P
- Norcross, Roger D
Publication details: Angewandte Chemie (International ed. in English) Nov 2001
In:
Angewandte Chemie (International ed. in English) vol. 40
Availability: No items available.
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10.
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4-Substituted-7-N-alkyl-N-acetyl 2-aminobenzothiazole amides: drug-like and non-xanthine based A2B adenosine receptor antagonists. [electronic resource] by
- Cheung, Adrian Wai-Hing
- Brinkman, John
- Firooznia, Fariborz
- Flohr, Alexander
- Grimsby, Joseph
- Gubler, Mary Lou
- Guertin, Kevin
- Hamid, Rachid
- Marcopulos, Nicholas
- Norcross, Roger D
- Qi, Lida
- Ramsey, Gwendolyn
- Tan, Jenny
- Wen, Yang
- Sarabu, Ramakanth
Producer: 20101207
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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11.
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Stereocontrolled Total Synthesis of (+)-Altohyrtin A/Spongistatin 1. [electronic resource] by
- Paterson, Ian
- Chen, David Y-K
- Coster, Mark J
- Aceña, Jose L
- Bach, Jordi
- Gibson, Karl R
- Keown, Linda E
- Oballa, Renata M
- Trieselmann, Thomas
- Wallace, Debra J
- Hodgson, Andrew P
- Norcross, Roger D
Publication details: Angewandte Chemie (International ed. in English) Nov 2001
In:
Angewandte Chemie (International ed. in English) vol. 40
Availability: No items available.
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12.
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Brain-specific overexpression of trace amine-associated receptor 1 alters monoaminergic neurotransmission and decreases sensitivity to amphetamine. [electronic resource] by
- Revel, Florent G
- Meyer, Claas A
- Bradaia, Amyaouch
- Jeanneau, Karine
- Calcagno, Eleonora
- André, Cédric B
- Haenggi, Markus
- Miss, Marie-Thérèse
- Galley, Guido
- Norcross, Roger D
- Invernizzi, Roberto W
- Wettstein, Joseph G
- Moreau, Jean-Luc
- Hoener, Marius C
Producer: 20130322
In:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology vol. 37
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13.
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Incretin-like effects of small molecule trace amine-associated receptor 1 agonists. [electronic resource] by
- Raab, Susanne
- Wang, Haiyan
- Uhles, Sabine
- Cole, Nadine
- Alvarez-Sanchez, Ruben
- Künnecke, Basil
- Ullmer, Christoph
- Matile, Hugues
- Bedoucha, Marc
- Norcross, Roger D
- Ottaway-Parker, Nickki
- Perez-Tilve, Diego
- Conde Knape, Karin
- Tschöp, Matthias H
- Hoener, Marius C
- Sewing, Sabine
Producer: 20160204
In:
Molecular metabolism vol. 5
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Discovery of benzoylisoindolines as a novel class of potent, selective and orally active GlyT1 inhibitors. [electronic resource] by
- Pinard, Emmanuel
- Alberati, Daniela
- Bender, Markus
- Borroni, Edilio
- Brom, Virginie
- Burner, Serge
- Fischer, Holger
- Hainzl, Dominik
- Halm, Remy
- Hauser, Nicole
- Jolidon, Synèse
- Lengyel, Judith
- Marty, Hans-Peter
- Meyer, Thierry
- Moreau, Jean-Luc
- Mory, Roland
- Narquizian, Robert
- Norcross, Roger D
- Schmid, Philipp
- Wermuth, Roger
- Zimmerli, Daniel
Producer: 20110223
In:
Bioorganic & medicinal chemistry letters vol. 20
Availability: No items available.
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15.
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Trace amine-associated receptor 1 partial agonism reveals novel paradigm for neuropsychiatric therapeutics. [electronic resource] by
- Revel, Florent G
- Moreau, Jean-Luc
- Gainetdinov, Raul R
- Ferragud, Antonio
- Velázquez-Sánchez, Clara
- Sotnikova, Tatyana D
- Morairty, Stephen R
- Harmeier, Anja
- Groebke Zbinden, Katrin
- Norcross, Roger D
- Bradaia, Amyaouch
- Kilduff, Thomas S
- Biemans, Barbara
- Pouzet, Bruno
- Caron, Marc G
- Canales, Juan J
- Wallace, Tanya L
- Wettstein, Joseph G
- Hoener, Marius C
Producer: 20130423
In:
Biological psychiatry vol. 72
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16.
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Selective GlyT1 inhibitors: discovery of [4-(3-fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a promising novel medicine to treat schizophrenia. [electronic resource] by
- Pinard, Emmanuel
- Alanine, Alexander
- Alberati, Daniela
- Bender, Markus
- Borroni, Edilio
- Bourdeaux, Patrick
- Brom, Virginie
- Burner, Serge
- Fischer, Holger
- Hainzl, Dominik
- Halm, Remy
- Hauser, Nicole
- Jolidon, Synese
- Lengyel, Judith
- Marty, Hans-Peter
- Meyer, Thierry
- Moreau, Jean-Luc
- Mory, Roland
- Narquizian, Robert
- Nettekoven, Mathias
- Norcross, Roger D
- Puellmann, Bernd
- Schmid, Philipp
- Schmitt, Sebastien
- Stalder, Henri
- Wermuth, Roger
- Wettstein, Joseph G
- Zimmerli, Daniel
Producer: 20100708
In:
Journal of medicinal chemistry vol. 53
Availability: No items available.
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