Ultra-deep massively parallel sequencing with unique molecular identifier tagging achieves comparable performance to droplet digital PCR for detection and quantification of circulating tumor DNA from lung cancer patients. [electronic resource]
Producer: 20200416Description: e0226193 p. digitalISSN:- 1932-6203
- Adult
- Aged
- Aged, 80 and over
- Carcinoma, Non-Small-Cell Lung -- diagnosis
- Circulating Tumor DNA -- analysis
- DNA Barcoding, Taxonomic -- methods
- DNA Mutational Analysis -- methods
- DNA, Neoplasm -- analysis
- ErbB Receptors -- genetics
- Female
- GTP Phosphohydrolases -- genetics
- High-Throughput Nucleotide Sequencing -- methods
- Humans
- Limit of Detection
- Liquid Biopsy
- Lung Neoplasms -- diagnosis
- Male
- Membrane Proteins -- genetics
- Middle Aged
- Polymerase Chain Reaction -- methods
- Proto-Oncogene Proteins B-raf -- genetics
- Proto-Oncogene Proteins p21(ras) -- genetics
- Reproducibility of Results
- Sequence Tagged Sites
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Publication Type: Comparative Study; Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
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