Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970. [electronic resource]
Producer: 20150605Description: 5674-85 p. digitalISSN:- 1949-2553
- Animals
- Antineoplastic Combined Chemotherapy Protocols -- pharmacology
- Ataxia Telangiectasia Mutated Proteins -- antagonists & inhibitors
- Cell Line, Tumor
- Cisplatin -- administration & dosage
- DNA -- drug effects
- DNA Damage
- Drug Synergism
- Female
- Humans
- Isoxazoles -- pharmacology
- Mice
- Mice, SCID
- Phosphorylation
- Protein Kinase Inhibitors -- administration & dosage
- Pyrazines -- pharmacology
- Random Allocation
- Signal Transduction
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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