Stabilization of HIF-2α through redox regulation of mTORC2 activation and initiation of mRNA translation. [electronic resource]
Producer: 20130903Description: 3147-55 p. digitalISSN:- 1476-5594
- Animals
- Basic Helix-Loop-Helix Transcription Factors -- metabolism
- Carcinoma, Renal Cell -- genetics
- Cell Line, Tumor
- Cell Transformation, Neoplastic
- Enzyme Activation
- Eukaryotic Initiation Factor-4E -- metabolism
- Humans
- Mechanistic Target of Rapamycin Complex 2
- Mice
- Multiprotein Complexes -- metabolism
- NADPH Oxidases -- genetics
- Neoplasm Transplantation
- Oxidation-Reduction
- Protein Biosynthesis
- RNA, Messenger -- genetics
- TOR Serine-Threonine Kinases -- metabolism
- Transplantation, Heterologous
- Von Hippel-Lindau Tumor Suppressor Protein -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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