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  2. Details for: Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.
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Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides. [electronic resource]

By:
  • Russell, Stephanie
Contributor(s):
  • Rahmani, Raphaël
  • Jones, Amy J
  • Newson, Harriet L
  • Neilde, Kevin
  • Cotillo, Ignacio
  • Rahmani Khajouei, Marzieh
  • Ferrins, Lori
  • Qureishi, Sana
  • Nguyen, Nghi
  • Martinez-Martinez, Maria S
  • Weaver, Donald F
  • Kaiser, Marcel
  • Riley, Jennifer
  • Thomas, John
  • De Rycker, Manu
  • Read, Kevin D
  • Flematti, Gavin R
  • Ryan, Eileen
  • Tanghe, Scott
  • Rodriguez, Ana
  • Charman, Susan A
  • Kessler, Albane
  • Avery, Vicky M
  • Baell, Jonathan B
  • Piggott, Matthew J
Producer: 20170608Description: 9686-9720 p. digitalISSN:
  • 1520-4804
Subject(s):
  • 14-alpha Demethylase Inhibitors -- chemical synthesis
  • Animals
  • Drug Discovery
  • Humans
  • Mice
  • Molecular Structure
  • Parasitic Sensitivity Tests
  • Sterol 14-Demethylase -- metabolism
  • Structure-Activity Relationship
  • Trypanocidal Agents -- chemical synthesis
  • Trypanosoma brucei brucei -- drug effects
  • Trypanosoma cruzi -- drug effects
Online resources:
  • Available from publisher's website
In: Journal of medicinal chemistry vol. 59
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Publication Type: Journal Article

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Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides.

APA

Russell S., Rahmani R., Jones A. J., Newson H. L., Neilde K., Cotillo I., Rahmani Khajouei M., Ferrins L., Qureishi S., Nguyen N., Martinez-Martinez M. S., Weaver D. F., Kaiser M., Riley J., Thomas J., De Rycker M., Read K. D., Flematti G. R., Ryan E., Tanghe S., Rodriguez A., Charman S. A., Kessler A., Avery V. M., Baell J. B. & Piggott M. J. (20170608). Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides. : Journal of medicinal chemistry.

Chicago

Russell Stephanie, Rahmani Raphaël, Jones Amy J, Newson Harriet L, Neilde Kevin, Cotillo Ignacio, Rahmani Khajouei Marzieh, Ferrins Lori, Qureishi Sana, Nguyen Nghi, Martinez-Martinez Maria S, Weaver Donald F, Kaiser Marcel, Riley Jennifer, Thomas John, De Rycker Manu, Read Kevin D, Flematti Gavin R, Ryan Eileen, Tanghe Scott, Rodriguez Ana, Charman Susan A, Kessler Albane, Avery Vicky M, Baell Jonathan B and Piggott Matthew J. 20170608. Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides. : Journal of medicinal chemistry.

Harvard

Russell S., Rahmani R., Jones A. J., Newson H. L., Neilde K., Cotillo I., Rahmani Khajouei M., Ferrins L., Qureishi S., Nguyen N., Martinez-Martinez M. S., Weaver D. F., Kaiser M., Riley J., Thomas J., De Rycker M., Read K. D., Flematti G. R., Ryan E., Tanghe S., Rodriguez A., Charman S. A., Kessler A., Avery V. M., Baell J. B. and Piggott M. J. (20170608). Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides. : Journal of medicinal chemistry.

MLA

Russell Stephanie, Rahmani Raphaël, Jones Amy J, Newson Harriet L, Neilde Kevin, Cotillo Ignacio, Rahmani Khajouei Marzieh, Ferrins Lori, Qureishi Sana, Nguyen Nghi, Martinez-Martinez Maria S, Weaver Donald F, Kaiser Marcel, Riley Jennifer, Thomas John, De Rycker Manu, Read Kevin D, Flematti Gavin R, Ryan Eileen, Tanghe Scott, Rodriguez Ana, Charman Susan A, Kessler Albane, Avery Vicky M, Baell Jonathan B and Piggott Matthew J. Hit-to-Lead Optimization of a Novel Class of Potent, Broad-Spectrum Trypanosomacides. : Journal of medicinal chemistry. 20170608.

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