Nicotine affects the signaling of the death pathway, reducing the response of head and neck cancer cell lines to DNA damaging agents. [electronic resource]
Producer: 20011025Description: 860-70 p. digitalISSN:- 1043-3074
- Antineoplastic Agents -- pharmacology
- Apoptosis -- drug effects
- CCAAT-Enhancer-Binding Proteins -- metabolism
- Colony-Forming Units Assay
- DNA Adducts -- drug effects
- DNA Damage
- DNA Fragmentation -- drug effects
- Head and Neck Neoplasms -- drug therapy
- Humans
- JNK Mitogen-Activated Protein Kinases
- MAP Kinase Kinase 4
- Mitogen-Activated Protein Kinase Kinases -- metabolism
- Nicotine -- pharmacology
- Nicotinic Agonists -- pharmacology
- Signal Transduction -- drug effects
- Transcription Factor CHOP
- Transcription Factors -- metabolism
- Tumor Cells, Cultured
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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