Aminoadamantanes containing monoterpene-derived fragments as potent tyrosyl-DNA phosphodiesterase 1 inhibitors. [electronic resource]
Producer: 20181211Description: 392-399 p. digitalISSN:- 1090-2120
- Adamantane -- analogs & derivatives
- Amines -- chemical synthesis
- Antineoplastic Agents -- chemical synthesis
- Binding Sites
- Drug Screening Assays, Antitumor
- Drug Synergism
- HCT116 Cells
- Humans
- Molecular Docking Simulation
- Monoterpenes -- chemical synthesis
- Phosphodiesterase Inhibitors -- chemical synthesis
- Phosphoric Diester Hydrolases -- chemistry
- Stereoisomerism
- Topotecan -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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