Synthesis and biological evaluation of 14-alkoxymorphinans. 1. Highly potent opioid agonists in the series of (-)-14-methoxy-N-methylmorphinan-6-ones. [electronic resource]
Producer: 19850122Description: 1575-9 p. digitalISSN:- 0022-2623
- Analgesia
- Animals
- Binding, Competitive
- Biological Assay
- Brain -- metabolism
- Cell Membrane -- metabolism
- Drug Evaluation, Preclinical
- Humans
- Indicators and Reagents
- Mice
- Morphinans -- chemical synthesis
- Morphine -- pharmacology
- Naloxone -- metabolism
- Narcotic Antagonists -- chemical synthesis
- Rabbits
- Rats
- Receptors, Opioid -- drug effects
- Respiration -- drug effects
- Structure-Activity Relationship
- Substance Withdrawal Syndrome
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Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
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