The development of a modified human IFN-alpha2b linked to the Fc portion of human IgG1 as a novel potential therapeutic for the treatment of hepatitis C virus infection. [electronic resource]
Producer: 20050211Description: 560-72 p. digitalISSN:- 1079-9907
- Amino Acid Sequence
- Antiviral Agents -- chemistry
- Cell Line
- Epitopes, T-Lymphocyte -- analysis
- Hepacivirus -- drug effects
- Hepatitis C, Chronic -- drug therapy
- Humans
- Immunoglobulin Fc Fragments -- genetics
- Immunoglobulin Fragments -- immunology
- Immunoglobulin G -- genetics
- Interferon alpha-2
- Interferon-alpha -- chemistry
- Molecular Sequence Data
- Peptides -- genetics
- Point Mutation
- Recombinant Fusion Proteins -- immunology
- Recombinant Proteins
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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