Results
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Bcl-2/Bcl-xL inhibition increases the efficacy of MEK inhibition alone and in combination with PI3 kinase inhibition in lung and pancreatic tumor models. [electronic resource] by
- Tan, Nguyen
- Wong, Maureen
- Nannini, Michelle A
- Hong, Rebecca
- Lee, Leslie B
- Price, Stephen
- Williams, Karen
- Savy, Pierre Pascal
- Yue, Peng
- Sampath, Deepak
- Settleman, Jeffrey
- Fairbrother, Wayne J
- Belmont, Lisa D
Producer: 20140224
In:
Molecular cancer therapeutics vol. 12
Availability: No items available.
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8.
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Canonical hedgehog signaling augments tumor angiogenesis by induction of VEGF-A in stromal perivascular cells. [electronic resource] by
- Chen, Weiwei
- Tang, Tracy
- Eastham-Anderson, Jeff
- Dunlap, Debra
- Alicke, Bruno
- Nannini, Michelle
- Gould, Stephen
- Yauch, Robert
- Modrusan, Zora
- DuPree, Kelly J
- Darbonne, Walter C
- Plowman, Greg
- de Sauvage, Frederic J
- Callahan, Christopher A
Producer: 20110826
In:
Proceedings of the National Academy of Sciences of the United States of America vol. 108
Availability: No items available.
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9.
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The corticotropin-releasing factor/urocortin system and alcohol. [electronic resource] by
- Ryabinin, Andrey E
- Bachtell, Ryan K
- Heinrichs, Stephen C
- Lee, Soon
- Rivier, Catherine
- Olive, M Foster
- Mehmert, Kristin K
- Camarini, Rosana
- Kim, Joseph A
- Koenig, Heather N
- Nannini, Michelle A
- Hodge, Clyde W
- Roberts, Amanda J
- Koob, George F
Producer: 20021029
In:
Alcoholism, clinical and experimental research vol. 26
Availability: No items available.
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10.
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Strategically Timing Inhibition of Phosphatidylinositol 3-Kinase to Maximize Therapeutic Index in Estrogen Receptor Alpha-Positive, PIK3CA-Mutant Breast Cancer. [electronic resource] by
- Yang, Wei
- Hosford, Sarah R
- Dillon, Lloye M
- Shee, Kevin
- Liu, Stephanie C
- Bean, Jennifer R
- Salphati, Laurent
- Pang, Jodie
- Zhang, Xiaolin
- Nannini, Michelle A
- Demidenko, Eugene
- Bates, Darcy
- Lewis, Lionel D
- Marotti, Jonathan D
- Eastman, Alan R
- Miller, Todd W
Producer: 20180116
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 22
Availability: No items available.
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11.
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Modeling targeted inhibition of MEK and PI3 kinase in human pancreatic cancer. [electronic resource] by
- Junttila, Melissa R
- Devasthali, Vidusha
- Cheng, Jason H
- Castillo, Joseph
- Metcalfe, Ciara
- Clermont, Anne C
- Otter, Douglas Den
- Chan, Emily
- Bou-Reslan, Hani
- Cao, Tim
- Forrest, William
- Nannini, Michelle A
- French, Dorothy
- Carano, Richard
- Merchant, Mark
- Hoeflich, Klaus P
- Singh, Mallika
Producer: 20150928
In:
Molecular cancer therapeutics vol. 14
Availability: No items available.
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12.
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Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models. [electronic resource] by
- O'Brien, Thomas
- Oeh, Jason
- Xiao, Yang
- Liang, Xiaorong
- Vanderbilt, Alexander
- Qin, Ann
- Yang, Lulu
- Lee, Leslie B
- Ly, Justin
- Cosino, Ely
- LaCap, Jennifer A
- Ogasawara, Annie
- Williams, Simon
- Nannini, Michelle
- Liederer, Bianca M
- Jackson, Peter
- Dragovich, Peter S
- Sampath, Deepak
Producer: 20140908
In:
Neoplasia (New York, N.Y.) vol. 15
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13.
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The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function. [electronic resource] by
- Hernandez, Sairy
- Qing, Jing
- Thibodeau, Rebecca Hong
- Du, Xiangnan
- Park, Summer
- Lee, Hyang-Mi
- Xu, Min
- Oh, Soyoung
- Navarro, Armando
- Roose-Girma, Meron
- Newman, Robert J
- Warming, Soren
- Nannini, Michelle
- Sampath, Deepak
- Kim, Jeong M
- Grogan, Jane L
- Mellman, Ira
Producer: 20200108
In:
Cell reports vol. 25
Availability: No items available.
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14.
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Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State. [electronic resource] by
- Daemen, Anneleen
- Liu, Bonnie
- Song, Kyung
- Kwong, Mandy
- Gao, Min
- Hong, Rebecca
- Nannini, Michelle
- Peterson, David
- Liederer, Bianca M
- de la Cruz, Cecile
- Sangaraju, Dewakar
- Jaochico, Allan
- Zhao, Xiaofeng
- Sandoval, Wendy
- Hunsaker, Thomas
- Firestein, Ron
- Latham, Sheerin
- Sampath, Deepak
- Evangelista, Marie
- Hatzivassiliou, Georgia
Producer: 20191004
In:
Cell metabolism vol. 28
Availability: No items available.
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15.
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Evaluation and clinical analyses of downstream targets of the Akt inhibitor GDC-0068. [electronic resource] by
- Yan, Yibing
- Serra, Violeta
- Prudkin, Ludmila
- Scaltriti, Maurizio
- Murli, Sumati
- Rodríguez, Olga
- Guzman, Marta
- Sampath, Deepak
- Nannini, Michelle
- Xiao, Yuanyuan
- Wagle, Marie-Claire
- Wu, Jenny Q
- Wongchenko, Matthew
- Hampton, Garret
- Ramakrishnan, Vanitha
- Lackner, Mark R
- Saura, Cristina
- Roda, Desamparados
- Cervantes, Andrés
- Tabernero, Josep
- Patel, Premal
- Baselga, José
Producer: 20140826
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 19
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16.
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Targeting activated Akt with GDC-0068, a novel selective Akt inhibitor that is efficacious in multiple tumor models. [electronic resource] by
- Lin, Jie
- Sampath, Deepak
- Nannini, Michelle A
- Lee, Brian B
- Degtyarev, Michael
- Oeh, Jason
- Savage, Heidi
- Guan, Zhengyu
- Hong, Rebecca
- Kassees, Robert
- Lee, Leslie B
- Risom, Tyler
- Gross, Stefan
- Liederer, Bianca M
- Koeppen, Hartmut
- Skelton, Nicholas J
- Wallin, Jeffrey J
- Belvin, Marcia
- Punnoose, Elizabeth
- Friedman, Lori S
- Lin, Kui
Producer: 20130927
In:
Clinical cancer research : an official journal of the American Association for Cancer Research vol. 19
Availability: No items available.
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17.
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A First-in-Human Phase I Study of the ATP-Competitive AKT Inhibitor Ipatasertib Demonstrates Robust and Safe Targeting of AKT in Patients with Solid Tumors. [electronic resource] by
- Saura, Cristina
- Roda, Desamparados
- Roselló, Susana
- Oliveira, Mafalda
- Macarulla, Teresa
- Pérez-Fidalgo, José Alejandro
- Morales-Barrera, Rafael
- Sanchis-García, Juan Manuel
- Musib, Luna
- Budha, Nageshwar
- Zhu, Jin
- Nannini, Michelle
- Chan, Wai Y
- Sanabria Bohórquez, Sandra M
- Meng, Raymond D
- Lin, Kui
- Yan, Yibing
- Patel, Premal
- Baselga, José
- Tabernero, Josep
- Cervantes, Andrés
Producer: 20171102
In:
Cancer discovery vol. 7
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18.
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Unexpected equivalent potency of a constrained chromene enantiomeric pair rationalized by co-crystal structures in complex with estrogen receptor alpha. [electronic resource] by
- Zhang, Birong
- Kiefer, James R
- Blake, Robert A
- Chang, Jae H
- Hartman, Steven
- Ingalla, Ellen Rei
- Kleinheinz, Tracy
- Mody, Vidhi
- Nannini, Michelle
- Ortwine, Daniel F
- Ran, Yingqing
- Sambrone, Amy
- Sampath, Deepak
- Vinogradova, Maia
- Zhong, Yu
- Nwachukwu, Jerome C
- Nettles, Kendall W
- Lai, Tommy
- Liao, Jiangpeng
- Zheng, Xiaoping
- Chen, Hai
- Wang, Xiaojing
- Liang, Jun
Producer: 20200305
In:
Bioorganic & medicinal chemistry letters vol. 29
Availability: No items available.
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19.
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Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models. [electronic resource] by
- Singh, Mallika
- Lima, Anthony
- Molina, Rafael
- Hamilton, Patricia
- Clermont, Anne C
- Devasthali, Vidusha
- Thompson, Jennifer D
- Cheng, Jason H
- Bou Reslan, Hani
- Ho, Calvin C K
- Cao, Timothy C
- Lee, Chingwei V
- Nannini, Michelle A
- Fuh, Germaine
- Carano, Richard A D
- Koeppen, Hartmut
- Yu, Ron X
- Forrest, William F
- Plowman, Gregory D
- Johnson, Leisa
Producer: 20100913
In:
Nature biotechnology vol. 28
Availability: No items available.
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20.
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Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models. [electronic resource] by
- Singh, Mallika
- Couto, Suzana S
- Forrest, William F
- Lima, Anthony
- Cheng, Jason H
- Molina, Rafael
- Long, Jason E
- Hamilton, Patricia
- McNutt, Angela
- Kasman, Ian
- Nannini, Michelle A
- Reslan, Hani Bou
- Cao, Tim C
- Ho, Calvin C K
- Barck, Kai H
- Carano, Richard A D
- Foreman, Oded
- Eastham-Anderson, Jeffrey
- Jubb, Adrian M
- Ferrara, Napoleone
- Johnson, Leisa
Producer: 20120925
In:
The Journal of pathology vol. 227
Availability: No items available.
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