Microinjection of carbachol in the lateral hypothalamus produces opposing actions on nociception mediated by alpha(1)- and alpha(2)-adrenoceptors. [electronic resource]
Producer: 20011011Description: 27-36 p. digitalISSN:- 0006-8993
- Adrenergic alpha-Antagonists -- pharmacology
- Analgesia
- Animals
- Carbachol -- pharmacology
- Cholinergic Agonists -- pharmacology
- Dose-Response Relationship, Drug
- Efferent Pathways -- drug effects
- Female
- Hypothalamic Area, Lateral -- drug effects
- Injections, Spinal
- Nociceptors -- drug effects
- Norepinephrine -- metabolism
- Pain -- metabolism
- Pain Measurement -- drug effects
- Pons -- drug effects
- Posterior Horn Cells -- drug effects
- Rats
- Rats, Sprague-Dawley
- Receptors, Adrenergic, alpha-1 -- drug effects
- Receptors, Adrenergic, alpha-2 -- drug effects
- Receptors, Opioid, mu -- drug effects
- Substance P -- metabolism
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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