Saredutant, an NK2 receptor antagonist, has both antidepressant-like effects and synergizes with desipramine in an animal model of depression. [electronic resource]
Producer: 20100930Description: 206-10 p. digitalISSN:- 1873-5177
- Animals
- Antidepressive Agents -- administration & dosage
- Benzamides -- administration & dosage
- Depression -- drug therapy
- Desipramine -- administration & dosage
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Drug Synergism
- Drug Therapy, Combination
- Piperidines -- administration & dosage
- Rats
- Rats, Inbred Strains
- Receptors, Neurokinin-2 -- antagonists & inhibitors
- Social Behavior
- Swimming
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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