Use of Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Axitinib Exposure: A Fresh Approach to Precision Dosing in Oncology. [electronic resource]
Producer: 20200825Description: 872-879 p. digitalISSN:- 1552-4604
- Albumins -- metabolism
- Axitinib -- pharmacokinetics
- Biological Variation, Population -- drug effects
- Biomarkers
- Biomarkers, Pharmacological
- Cytochrome P-450 CYP3A -- metabolism
- Drug Dosage Calculations
- Humans
- Linear Models
- Models, Biological
- Neoplasms -- drug therapy
- Receptors, Vascular Endothelial Growth Factor -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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