A novel gamma -secretase assay based on detection of the putative C-terminal fragment-gamma of amyloid beta protein precursor. [electronic resource]
Producer: 20010208Description: 481-7 p. digitalISSN:- 0021-9258
- Alzheimer Disease -- enzymology
- Amyloid Precursor Protein Secretases
- Amyloid beta-Peptides -- analysis
- Amyloid beta-Protein Precursor -- metabolism
- Animals
- Brain -- cytology
- Caspase 3
- Caspases -- metabolism
- Cells, Cultured
- Detergents -- pharmacology
- Endopeptidases -- analysis
- Guinea Pigs
- Hydrogen-Ion Concentration
- Membrane Proteins -- analysis
- Molecular Weight
- Pepstatins -- pharmacology
- Peptide Fragments -- analysis
- Phenanthrolines -- pharmacology
- Protease Inhibitors -- pharmacology
- Protein Processing, Post-Translational -- drug effects
- Solubility -- drug effects
- Subcellular Fractions -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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