Ubiquitously expressed hematological and neurological expressed 1 downregulates Akt-mediated GSK3β signaling, and its knockdown results in deregulated G2/M transition in prostate cells. [electronic resource]
Producer: 20110804Description: 419-29 p. digitalISSN:- 1557-7430
- Amino Acid Sequence
- Cell Cycle
- Cell Line, Tumor
- Cell Movement
- Cell Nucleus -- metabolism
- Chromones -- pharmacology
- Cloning, Molecular
- Cyclin B1 -- metabolism
- Cyclin D1 -- metabolism
- Down-Regulation
- Epidermal Growth Factor -- pharmacology
- Flavonoids -- pharmacology
- Gene Knockdown Techniques
- Glycogen Synthase Kinase 3 -- metabolism
- Glycogen Synthase Kinase 3 beta
- Humans
- Male
- Molecular Sequence Data
- Morpholines -- pharmacology
- Neoplasm Proteins -- genetics
- Nerve Tissue Proteins -- genetics
- Phosphorylation
- Prostate -- cytology
- Proto-Oncogene Proteins c-akt -- metabolism
- Signal Transduction
- Tetraploidy
- Up-Regulation
- beta Catenin -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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