Overproduction of cyclin D1 is dependent on activated mTORC1 signal in nasopharyngeal carcinoma: implication for therapy. [electronic resource]
Producer: 20090514Description: 47-56 p. digitalISSN:- 1872-7980
- Adaptor Proteins, Signal Transducing -- metabolism
- Adult
- Apoptosis
- Carcinoma -- metabolism
- Case-Control Studies
- Cell Cycle Proteins
- Cell Line, Tumor
- Cell Survival
- Cyclin D1 -- metabolism
- Dose-Response Relationship, Drug
- Female
- Humans
- Male
- Middle Aged
- Multiprotein Complexes -- metabolism
- Nasopharyngeal Neoplasms -- metabolism
- Phosphoproteins -- metabolism
- Phosphorylation
- Protein Kinases -- genetics
- RNA Interference
- RNA, Small Interfering -- metabolism
- Signal Transduction -- drug effects
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases
- Time Factors
- Transfection
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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