Pretreatment with interleukin-6 small interfering RNA can improve the survival rate of polymicrobial cecal ligation and puncture mice by down regulating interleukin-6 production. [electronic resource]
Producer: 20121116Description: 76-83 p. digitalISSN:- 1879-0712
- Alanine Transaminase -- metabolism
- Animals
- Anti-Bacterial Agents -- pharmacology
- Blood Urea Nitrogen
- Cecum -- drug effects
- Down-Regulation -- drug effects
- Interleukin-6 -- biosynthesis
- Ligation -- adverse effects
- Male
- Mice
- Mice, Inbred ICR
- Punctures -- adverse effects
- RNA, Small Interfering -- genetics
- Receptors, Complement -- genetics
- Sepsis -- etiology
- Survival Analysis
- Survival Rate
- T-Lymphocytes, Helper-Inducer -- drug effects
- Time Factors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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