Impact of the enfuvirtide resistance mutation N43D and the associated baseline polymorphism E137K on peptide sensitivity and six-helix bundle structure. [electronic resource]
Producer: 20100507Description: 6662-70 p. digitalISSN:- 1520-4995
- Binding Sites
- Circular Dichroism
- Crystallography, X-Ray
- Drug Resistance, Viral -- genetics
- Enfuvirtide
- HIV Envelope Protein gp41 -- chemistry
- HIV Fusion Inhibitors -- pharmacology
- HIV-1 -- drug effects
- Humans
- Hydrogen Bonding
- Inhibitory Concentration 50
- Models, Molecular
- Mutation
- Peptide Fragments -- pharmacology
- Polymorphism, Genetic
- Protein Structure, Secondary
- Protein Structure, Tertiary
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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