New non-peptide endothelin-A receptor antagonists: synthesis, biological properties, and structure-activity relationships of 5-(dimethylamino)-N-pyridyl-,-N-pyrimidinyl-,-N-pyridazinyl-, and -N-pyrazinyl-1-naphthalenesulfonamides. [electronic resource]
Producer: 19970501Description: 996-1004 p. digitalISSN:- 0022-2623
- Animals
- Antihypertensive Agents -- chemical synthesis
- Blood Pressure -- drug effects
- Dansyl Compounds -- chemical synthesis
- Endothelin Receptor Antagonists
- Endothelin-1
- Endothelins -- antagonists & inhibitors
- Guinea Pigs
- Magnetic Resonance Spectroscopy
- Male
- Molecular Structure
- Protein Binding
- Protein Precursors -- antagonists & inhibitors
- Rats
- Rats, Wistar
- Receptor, Endothelin A
- Receptors, Endothelin -- metabolism
- Structure-Activity Relationship
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Publication Type: Journal Article
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