Preclinical analysis of MTOR complex 1/2 inhibition in diffuse intrinsic pontine glioma. [electronic resource]
Producer: 20180905Description: 455-464 p. digitalISSN:- 1791-2431
- Antineoplastic Agents -- pharmacology
- Benzamides
- Brain Stem Neoplasms -- drug therapy
- Cell Culture Techniques
- Cell Cycle -- drug effects
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Everolimus -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Glioma -- drug therapy
- Humans
- Mechanistic Target of Rapamycin Complex 1 -- antagonists & inhibitors
- Mechanistic Target of Rapamycin Complex 2 -- antagonists & inhibitors
- Morpholines -- pharmacology
- Phosphorylation -- drug effects
- Proto-Oncogene Proteins c-akt -- metabolism
- Pyrimidines
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Publication Type: Comparative Study; Journal Article
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