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Synthesis and Pharmacological Characterization of Novel trans-Cyclopropylmethyl-Linked Bivalent Ligands That Exhibit Selectivity and Allosteric Pharmacology at the Dopamine D [electronic resource] by
- Kumar, Vivek
- Moritz, Amy E
- Keck, Thomas M
- Bonifazi, Alessandro
- Ellenberger, Michael P
- Sibley, Christopher D
- Free, R Benjamin
- Shi, Lei
- Lane, J Robert
- Sibley, David R
- Newman, Amy Hauck
Producer: 20170616
In:
Journal of medicinal chemistry vol. 60
Availability: No items available.
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9.
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A structural basis for how ligand binding site changes can allosterically regulate GPCR signaling and engender functional selectivity. [electronic resource] by
- Sanchez-Soto, Marta
- Verma, Ravi Kumar
- Willette, Blair K A
- Gonye, Elizabeth C
- Moore, Annah M
- Moritz, Amy E
- Boateng, Comfort A
- Yano, Hideaki
- Free, R Benjamin
- Shi, Lei
- Sibley, David R
Producer: 20210201
In:
Science signaling vol. 13
Availability: No items available.
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10.
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Structure-Activity Investigation of a G Protein-Biased Agonist Reveals Molecular Determinants for Biased Signaling of the D [electronic resource] by
- Chun, Lani S
- Vekariya, Rakesh H
- Free, R Benjamin
- Li, Yun
- Lin, Da-Ting
- Su, Ping
- Liu, Fang
- Namkung, Yoon
- Laporte, Stephane A
- Moritz, Amy E
- Aubé, Jeffrey
- Frankowski, Kevin J
- Sibley, David R
Publication details: Frontiers in synaptic neuroscience 2018
In:
Frontiers in synaptic neuroscience vol. 10
Availability: No items available.
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Investigation of the binding and functional properties of extended length D3 dopamine receptor-selective antagonists. [electronic resource] by
- Furman, Cheryse A
- Roof, Rebecca A
- Moritz, Amy E
- Miller, Brittney N
- Doyle, Trevor B
- Free, R Benjamin
- Banala, Ashwini K
- Paul, Noel M
- Kumar, Vivek
- Sibley, Christopher D
- Newman, Amy Hauck
- Sibley, David R
Producer: 20160608
In:
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology vol. 25
Availability: No items available.
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Discovery, Optimization, and Characterization of ML417: A Novel and Highly Selective D [electronic resource] by
- Moritz, Amy E
- Free, R Benjamin
- Weiner, Warren S
- Akano, Emmanuel O
- Gandhi, Disha
- Abramyan, Ara
- Keck, Thomas M
- Ferrer, Marc
- Hu, Xin
- Southall, Noel
- Steiner, Joseph
- Aubé, Jeffrey
- Shi, Lei
- Frankowski, Kevin J
- Sibley, David R
Producer: 20201023
In:
Journal of medicinal chemistry vol. 63
Availability: No items available.
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13.
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Identification of Positive Allosteric Modulators of the D [electronic resource] by
- Luderman, Kathryn D
- Conroy, Jennie L
- Free, R Benjamin
- Southall, Noel
- Ferrer, Marc
- Sanchez-Soto, Marta
- Moritz, Amy E
- Willette, Blair K A
- Fyfe, Tim J
- Jain, Prashi
- Titus, Steve
- Hazelwood, Lisa A
- Aubé, Jeffrey
- Lane, J Robert
- Frankowski, Kevin J
- Sibley, David R
Producer: 20190416
In:
Molecular pharmacology vol. 94
Availability: No items available.
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14.
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Discovery and characterization of a G protein-biased agonist that inhibits β-arrestin recruitment to the D2 dopamine receptor. [electronic resource] by
- Free, R Benjamin
- Chun, Lani S
- Moritz, Amy E
- Miller, Brittney N
- Doyle, Trevor B
- Conroy, Jennie L
- Padron, Adrian
- Meade, Julie A
- Xiao, Jingbo
- Hu, Xin
- Dulcey, Andrés E
- Han, Yang
- Duan, Lihua
- Titus, Steve
- Bryant-Genevier, Melanie
- Barnaeva, Elena
- Ferrer, Marc
- Javitch, Jonathan A
- Beuming, Thijs
- Shi, Lei
- Southall, Noel T
- Marugan, Juan J
- Sibley, David R
Producer: 20140630
In:
Molecular pharmacology vol. 86
Availability: No items available.
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