Caveolin-1 is required for TGF-β-induced transactivation of the EGF receptor pathway in hepatocytes through the activation of the metalloprotease TACE/ADAM17. [electronic resource]
Producer: 20150604Description: e1326 p. digitalISSN:- 2041-4889
- ADAM Proteins -- genetics
- ADAM17 Protein
- Animals
- Apoptosis
- Caveolin 1 -- genetics
- Cells, Cultured
- Enzyme Activation
- ErbB Receptors -- genetics
- Female
- Hepatocytes -- enzymology
- Male
- Mice
- Mice, Knockout
- Phosphorylation
- Reactive Oxygen Species -- metabolism
- Signal Transduction
- Transcriptional Activation
- Transforming Growth Factor beta -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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