Catalysis leads to posttranslational inactivation of the type 1 deiodinase and alters its conformation. [electronic resource]
Producer: 20120920Description: 87-94 p. digitalISSN:- 1479-6805
- Biocatalysis -- drug effects
- Dose-Response Relationship, Drug
- Enzyme Activation -- drug effects
- Fluorescence Resonance Energy Transfer
- HEK293 Cells
- Hep G2 Cells
- Humans
- Iodide Peroxidase -- chemistry
- Luciferases -- genetics
- Luminescent Proteins -- genetics
- Mutation
- Propylthiouracil -- pharmacology
- Protein Conformation
- Protein Multimerization
- Protein Processing, Post-Translational -- drug effects
- Reverse Transcriptase Polymerase Chain Reaction
- Sonication
- Substrate Specificity
- Triiodothyronine -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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