A Potent Pan-TGFβ Neutralizing Monoclonal Antibody Elicits Cardiovascular Toxicity in Mice and Cynomolgus Monkeys. [electronic resource]
Producer: 20210601Description: 24-34 p. digitalISSN:- 1096-0929
- Animals
- Antibodies, Monoclonal, Humanized -- blood
- Antibodies, Neutralizing -- blood
- Cardiotoxicity
- Cardiovascular Diseases -- chemically induced
- Cell Line
- Female
- Heart -- drug effects
- Hemorrhage -- chemically induced
- Humans
- Macaca fascicularis
- Male
- Mice
- Myocardium -- metabolism
- Risk Assessment
- Time Factors
- Toxicity Tests
- Toxicokinetics
- Transforming Growth Factor beta -- antagonists & inhibitors
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Publication Type: Journal Article
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