Synthesis of 5-benzyl-2-phenylpyrazolo[1,5-a]pyrazin-4,6(5H,7H)-dione derivatives and discovery of an apoptosis inducer for H322 lung cancer cells. [electronic resource]
Producer: 20120824Description: 844-9 p. digitalISSN:- 1464-3405
- Antineoplastic Agents -- chemical synthesis
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Survival -- drug effects
- Crystallography, X-Ray
- Dose-Response Relationship, Drug
- Drug Discovery
- Drug Screening Assays, Antitumor
- Humans
- Models, Molecular
- Molecular Structure
- Pyrazines -- chemical synthesis
- Pyrazoles -- chemical synthesis
- Stereoisomerism
- Structure-Activity Relationship
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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