Induction of the mitochondrial permeability transition mediates the killing of HeLa cells by staurosporine. [electronic resource]
Producer: 20010426Description: 2459-66 p. digitalISSN:- 0008-5472
- Apoptosis -- drug effects
- Bongkrekic Acid -- pharmacology
- Caspase Inhibitors
- Cell Membrane Permeability -- drug effects
- Cell Survival -- drug effects
- Cytochrome c Group -- metabolism
- Enzyme Inhibitors -- pharmacology
- HeLa Cells
- Humans
- Malate Dehydrogenase -- metabolism
- Membrane Potentials -- drug effects
- Mitochondria -- drug effects
- Protein Serine-Threonine Kinases
- Proto-Oncogene Proteins -- biosynthesis
- Proto-Oncogene Proteins c-akt
- Proto-Oncogene Proteins c-bcl-2
- Staurosporine -- antagonists & inhibitors
- Transfection
- bcl-2-Associated X Protein
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Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.
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