Fluorinated 3,6,9-trisubstituted acridine derivatives as DNA interacting agents and topoisomerase inhibitors with A549 antiproliferative activity. [electronic resource]
Producer: 20210217Description: 103393 p. digitalISSN:- 1090-2120
- A549 Cells
- Acridines -- chemical synthesis
- Animals
- Antineoplastic Agents -- chemical synthesis
- Cattle
- Cell Proliferation -- drug effects
- DNA -- drug effects
- DNA Topoisomerases, Type I -- metabolism
- DNA Topoisomerases, Type II -- metabolism
- Dose-Response Relationship, Drug
- Drug Screening Assays, Antitumor
- Halogenation
- Humans
- Molecular Structure
- Structure-Activity Relationship
- Topoisomerase I Inhibitors -- chemical synthesis
- Topoisomerase II Inhibitors -- chemical synthesis
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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