NMR-based discovery of lead inhibitors that block DNA binding of the human papillomavirus E2 protein. [electronic resource]
Producer: 19971110Description: 3144-50 p. digitalISSN:- 0022-2623
- Antiviral Agents -- chemistry
- Binding Sites
- Biphenyl Compounds -- pharmacology
- Bovine papillomavirus 1
- Crystallography, X-Ray
- DNA -- metabolism
- DNA-Binding Proteins -- antagonists & inhibitors
- Drug Design
- Humans
- Ligands
- Magnetic Resonance Spectroscopy
- Models, Chemical
- Models, Molecular
- Papillomaviridae
- Protein Conformation
- Repressor Proteins -- metabolism
- Structure-Activity Relationship
- Trans-Activators -- metabolism
- Viral Proteins -- antagonists & inhibitors
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Publication Type: Journal Article
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