IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer. [electronic resource]
Producer: 20201026Description: 10353 p. digitalISSN:- 2045-2322
- Animals
- B7-H1 Antigen -- biosynthesis
- CD8-Positive T-Lymphocytes -- immunology
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Cell Line, Tumor
- Cytokines -- physiology
- Female
- Genes, ras
- Humans
- Immunity, Innate
- Interleukin-17 -- deficiency
- Lung Neoplasms -- drug therapy
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Molecular Targeted Therapy
- Neoplasm Proteins -- antagonists & inhibitors
- Neutrophils -- physiology
- Programmed Cell Death 1 Receptor -- antagonists & inhibitors
- Proto-Oncogene Proteins p21(ras) -- physiology
- Pulmonary Disease, Chronic Obstructive -- complications
- Recombinant Proteins -- pharmacology
- Tumor Microenvironment
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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